DNA Repair are growing in popularity
As we learn more about the role of DNA in the skin, the importance of protecting against DNA damage and how DNA repair enzymes help our skin in the repair process, the popularity is growing,
This google search history shows the growth over 7 years and the sheer volume of increased google search for DNA repair in the skin demonstrating that DNA is becoming a hot topic of conversation within the the skin care industry.
Where it all began?
The history of the repair of damaged DNA can be traced to the mid-1930s. Since then multiple DNA repair mechanisms, as well as other biological responses to DNA damage, have been discovered and their regulation has been studied. The Nobel Prize in Physiology or Medicine in 1962 was awarded to James Watson, Francis Crick and Maurice Wilkins for their discovery of the molecular structure of DNA.
Some 50 years later in 2015 the Nobel Prize for chemistry was awarded to three pioneering scientists for their work on DNA damage and repair mechanisms.
It was then Dr. Daniel B. Yarosh, PhD focused on the emerging sciences in skin care, such as DNA repair and the microbiome, and neuromarketing and evolutionary biology of beauty. In 1985, Dr. Yarosh founded the biotechnology company AGI Dermatics, with an emphasis on the commercial application of DNA repair. He is the inventor of Dimericine (T4N5 liposome lotion), which is a liposomal DNA repair enzyme for the prevention of skin cancer.
It is the basis of Dr. Daniel Yarosh that has founded Photozyme MD skincare.
Why is DNA Repair becoming so popular?
After decades of investigating the body’s DNA repair system, some of these findings have made their way into skincare formulations in the form of actives that purport to enhance cellular function, thereby aiding damaged DNA, and DNA repair enzymes—the latter of which are based heavily on the work of Daniel B. Yarosh, PhD.
In simple terms, endonucleases work by cutting out the damaged bits of DNA, which are then regenerated. Many studies in the last decade have shown that adding extra enzymes to the skin enhances the body’s innate mechanisms for repairing DNA damage. For one example, a 2010 study in the Journal of Drugs in Dermatology by Moy and colleagues at UCLA found that using a cream with DNA repair enzymes for 48 weeks significantly reduced actinic keratoses (scaly precancerous growths) in 17 people with severely sun-damaged skin
The results are being proven:
In addition, the importance of DNA repair enzymes have been highlighted as part of the 3 fundamental elements to skin protection. This pyramid below was published in 2014 in the journal of drugs and dermatology created by the field of aesthetic medicine.
It states that along with sunscreen and antioxidants, DNA Repair Enzymes make up the foundation of overall skin health.
BENEFITS OF DNA REPAIR IN THE SKIN?
- Works on optimising the health of our skin
- Reduces the appearance of fine lines and wrinkles
- Brightens dull skin by exfoliating at a cellular level
- Visibly reduce the signs of aging caused by sun damage
- Improves the appearance of age spots and evens out pigmentation
- Evens out skin tone and texture
- Enhances skin elasticity
ARE ALL DNA REPAIR PRODUCTS THE SAME?
The answer to this is no. There are 3 important factors to consider:
- The delivery used to bypass the skin barrier
- The use of the 3 ‘fundamental’ repair enzymes in combination
- And the percentage of the enzymes used
This is why we believe Photozyme MD Skincare is like no other.
Photozyme MD uses a liposomal delivery system. The enzymes are encapsulated in a proprietary liposome delivery system which drives them into the skin delivering the cargo into the cell. The enzymes search and only adhere to the damaged DNA strand. The cell’s natural process takes over, extracting the damage and replicating a healthy DNA strand.
Photozyme MD products include the 3 enzymes outlined below:
- Photolysomes, DNA repair enzymes extracted from plankton
- Mitosomes, DNA repair enzymes extracted from the mustard plant, Arabidopsis thalania
- Endosomes, DNA repair enzymes extracted from the marine microbe, Micrococcus lysate
And as Photozyme MD is a DNA focused brand, the 3 enzymes are in high concentrations.